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Anti-IL-6 Antibody (2H625)

Catalog No. TMAB-07672 Copy Product Info
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Anti-IL-6 Antibody (2H625) is a Mouse antibody targeting IL-6. Anti-IL-6 Antibody (2H625) can be used in WB.

Anti-IL-6 Antibody (2H625)

Copy Product Info
🥰Excellent
Catalog No. TMAB-07672

Anti-IL-6 Antibody (2H625) is a Mouse antibody targeting IL-6. Anti-IL-6 Antibody (2H625) can be used in WB.

Anti-IL-6 Antibody
(2H625)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IL-6 Antibody (2H625) is a Mouse antibody targeting IL-6. Anti-IL-6 Antibody (2H625) can be used in WB.
Ig Type
IgG
Clone
2H625
Reactivity
Human
Verified Activity
THP-1 (H) cells were treated with or without TPA (80 nM) and LPS (100 ng/ml,6 h) and Brefeldin A (300 ng/ml,3 h), 25 μg total protein per lane of cell lysates (see on figure) probed with IL-6 monoclonal antibody, unconjugated (TMAB-07672) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationSecreted.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011].
Antigen Details
Immunogen
Recombinant Protein: human IL-6 protein
Antigen Species
Human
Gene Name
IL6
Gene ID
Protein Name
Interleukin-6
Function
Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.
Chemical Properties
Molecular WeightTheoretical: 23 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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