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Anti-IGF1R Monoclonal Antibody (4C146)
(Synonyms: JTK13, IGFR, IGFIR, CD221) Copy Product Info
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Synonyms: JTK13, IGFR, IGFIR, CD221
Catalog No. TMAT-0747 Copy Product Info
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Anti-IGF1R Monoclonal Antibody (4C146) is a Mouse antibody targeting IGF1R. Anti-IGF1R Monoclonal Antibody (4C146) can be used in WB,FCM.
Anti-IGF1R Monoclonal Antibody
(4C146)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IGF1R Monoclonal Antibody (4C146) is a Mouse antibody targeting IGF1R. Anti-IGF1R Monoclonal Antibody (4C146) can be used in WB,FCM. |
| Synonyms | JTK13, IGFR, IGFIR, CD221 |
| Ig Type | IgG2a |
| Clone | 4C146 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human IGF1R (AA: extra(741-935)) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | IGF1R |
| Gene ID | |
| Protein Name | Insulin-like growth factor 1 receptor |
| Uniprot ID |
| Molecular Weight | Theoretical: 154.8 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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