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Anti-Human CD79b Antibody (4X293)

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Catalog No. TMAB-07420

Anti-Human CD79b Antibody (4X293) is a Mouse antibody targeting Human CD79b. Anti-Human CD79b Antibody (4X293) can be used in WB.

Anti-Human CD79b Antibody (4X293)

Anti-Human CD79b Antibody (4X293)

😃Good
Catalog No. TMAB-07420
Anti-Human CD79b Antibody (4X293) is a Mouse antibody targeting Human CD79b. Anti-Human CD79b Antibody (4X293) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Human CD79b Antibody (4X293) is a Mouse antibody targeting Human CD79b. Anti-Human CD79b Antibody (4X293) can be used in WB.
Ig Type
IgG1, k
Clone
4X293
Reactivity
Human
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCell membrane. Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
Tissue SpecificityB-cells.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CD79B
Antigen Species
Human
Gene Name
CD79B
Gene ID
974
Protein Name
B-cell antigen receptor complex-associated protein beta chain
Uniprot ID
P40259
Function
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Chemical Properties
Molecular WeightTheoretical: 23 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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