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Anti-human CD22 Antibody (6Q298)
😃Good
Catalog No. TMAB-07394
Anti-human CD22 Antibody (6Q298) is a Mouse antibody targeting human CD22. Anti-human CD22 Antibody (6Q298) can be used in FCM.
Anti-human CD22 Antibody (6Q298)
Anti-human CD22 Antibody (6Q298)
😃Good
Catalog No. TMAB-07394
Anti-human CD22 Antibody (6Q298) is a Mouse antibody targeting human CD22. Anti-human CD22 Antibody (6Q298) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $353 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-human CD22 Antibody (6Q298) is a Mouse antibody targeting human CD22. Anti-human CD22 Antibody (6Q298) can be used in FCM. |
| Ig Type | Mouse IgG1 |
| Clone | 6Q298 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | B-lymphocytes. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4). |
| Concentration | 1mg/ml |
| Research Background | Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome. [provided by Alliance of Genome Resources, Nov 2021] |
| Immunogen | KLH conjugated synthetic peptide: human CD22 |
| Antigen Species | Human |
| Gene Name | CD22 |
| Gene ID | |
| Protein Name | B-cell receptor CD22 |
| Uniprot ID | |
| Function | Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. |
| Molecular Weight | Theoretical: 91 kDa. Actual: 140 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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