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Anti-human CD16 Antibody (6K437)

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Catalog No. TMAB-07388

Anti-human CD16 Antibody (6K437) is a Mouse antibody targeting human CD16. Anti-human CD16 Antibody (6K437) can be used in FCM.

Anti-human CD16 Antibody (6K437)

Anti-human CD16 Antibody (6K437)

😃Good
Catalog No. TMAB-07388
Anti-human CD16 Antibody (6K437) is a Mouse antibody targeting human CD16. Anti-human CD16 Antibody (6K437) can be used in FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 μg$3527-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-human CD16 Antibody (6K437) is a Mouse antibody targeting human CD16. Anti-human CD16 Antibody (6K437) can be used in FCM.
Ig Type
Mouse IgG1, k
Clone
6K437
Reactivity
Human
Application
Recommended Dose
FCM: 1μg/Test
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCell membrane. Secreted. Exists also as a soluble receptor.
Tissue SpecificityExpressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4).
Research BackgroundThis gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
Antigen Details
Gene Name
FCGR3A
Gene ID
Protein Name
Low affinity immunoglobulin gamma Fc region receptor III-A
Function
Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
Chemical Properties
Molecular WeightTheoretical: 27 kDa. Actual: 50-65 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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