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Anti-human CD14 Antibody (3V163) is a Mouse antibody targeting human CD14. Anti-human CD14 Antibody (3V163) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $352 | 7-10 days | 7-10 days |
| Description | Anti-human CD14 Antibody (3V163) is a Mouse antibody targeting human CD14. Anti-human CD14 Antibody (3V163) can be used in FCM. |
| Ig Type | Mouse IgG1, k |
| Clone | 3V163 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1μl/Test |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4). |
| Research Background | The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010] |
| Gene Name | CD14 |
| Gene ID | |
| Protein Name | Monocyte differentiation antigen CD14 |
| Function | Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. |
| Molecular Weight | Theoretical: 35/40 kDa. Actual: 53-55 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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