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Anti-human CD11a Antibody (6R990)

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Catalog No. TMAB-07384

Anti-human CD11a Antibody (6R990) is a Mouse antibody targeting human CD11a. Anti-human CD11a Antibody (6R990) can be used in ICC/IF,FCM.

Anti-human CD11a Antibody (6R990)

Anti-human CD11a Antibody (6R990)

😃Good
Catalog No. TMAB-07384
Anti-human CD11a Antibody (6R990) is a Mouse antibody targeting human CD11a. Anti-human CD11a Antibody (6R990) can be used in ICC/IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 μg$3527-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-human CD11a Antibody (6R990) is a Mouse antibody targeting human CD11a. Anti-human CD11a Antibody (6R990) can be used in ICC/IF,FCM.
Ig Type
Mouse IgG2b, k
Clone
6R990
Reactivity
Human
Application
Recommended Dose
ICC/IF: 1:100-500; FCM: 1μg/Test
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
Tissue SpecificityLeukocytes.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4).
Research BackgroundITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Gene Name
ITGAL
Gene ID
Protein Name
Integrin alpha-L
Function
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
Chemical Properties
Molecular WeightTheoretical: 126 kDa. Actual: 180 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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