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Anti-human CD11a Antibody (6R990)

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Catalog No. TMAB-07384

Anti-human CD11a Antibody (6R990) is a Mouse antibody targeting human CD11a. Anti-human CD11a Antibody (6R990) can be used in ICC/IF,FCM.

Anti-human CD11a Antibody (6R990)

Anti-human CD11a Antibody (6R990)

Copy Product Info
😃Good
Catalog No. TMAB-07384
Anti-human CD11a Antibody (6R990) is a Mouse antibody targeting human CD11a. Anti-human CD11a Antibody (6R990) can be used in ICC/IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 μg$3527-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-human CD11a Antibody (6R990) is a Mouse antibody targeting human CD11a. Anti-human CD11a Antibody (6R990) can be used in ICC/IF,FCM.
Ig Type
Mouse IgG2b, k
Clone
6R990
Reactivity
Human
Verified Activity
1. Jurkat cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with (human CD11a) monoclonal Antibody, Unconjugated (TMAB-07384) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Mouse IgG antibody at 37°C for 90 minutes, DAPI (blue) was used to stain the cell nuclei.
2. scatter diagram showing human peripheral blood leukocytes stained with human CD11a. The cells were incubated with the antibody (TMAB-07384) for 30 min at 22°C. The secondary antibody used for 40 min at room temperature. Acquisition of >10,000 events was performed.
Application
Recommended Dose
ICC/IF: 1:100-500; FCM: 1μg/Test
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
Tissue SpecificityLeukocytes.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4).
Research BackgroundITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Gene Name
ITGAL
Gene ID
Protein Name
Integrin alpha-L
Function
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
Chemical Properties
Molecular WeightTheoretical: 126 kDa. Actual: 180 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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