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Anti-HSP90 beta Antibody (7Y854) is a Mouse antibody targeting HSP90 beta. Anti-HSP90 beta Antibody (7Y854) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,058 | 7-10 days | 7-10 days | |
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-HSP90 beta Antibody (7Y854) is a Mouse antibody targeting HSP90 beta. Anti-HSP90 beta Antibody (7Y854) can be used in WB. |
| Ig Type | IgG |
| Clone | 7Y854 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Sample: Lane 1: A431 (Human) Cell Lysate at 30 μg Lane 2: Hela (Human) Cell Lysate at 30 μg Lane 3: NIH/3T3 (Mouse) Cell Lysate at 30 μg Lane 4: K562 (Human) Cell Lysate at 30 μg Lane 5: HepG2 (Human) Cell Lysate at 30 μg Lane 6: U2os (Human) Cell Lysate at 30 μg Lane 7: A549 (Human) Cell Lysate at 30 μg Lane 8: HL60 (Human) Cell Lysate at 30 μg Lane 9: Jurkat (Human) Cell Lysate at 30 μg Lane 10: Testis (Mouse) Lysate at 40 μg Lane 11: Testis (Rat) Lysate at 40 μg Lane 12: Cerebrum (Mouse) Lysate at 40 μg Lane 13: Cerebrum (Rat) Lysate at 40 μg Primary: Anti-HSP90 beta (TMAB-07348) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 90 kD Observed band size: 86 kD 2. Sample: Hela KO HSP90 betA (Human) Cell Lysate at 30 μg Hela (Human) Cell Lysate at 30 μg Primary: Anti-HSP90 beta (TMAB-07348) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse t 1/20000 dilution Predicted band size: 84 kD Observed band size: 84 kD |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq, Dec 2012]. |
| Immunogen | KLH conjugated synthetic peptide: human HSP90 beta |
| Antigen Species | Human |
| Gene Name | HSP90AB1 |
| Gene ID | |
| Protein Name | Heat shock protein HSP 90-beta |
| Uniprot ID | |
| Function | Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. |
| Molecular Weight | Theoretical: 84 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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