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Anti-HP1 gamma Antibody (3Y560)

Catalog No. TMAB-07266 Copy Product Info
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Anti-HP1 gamma Antibody (3Y560) is a Mouse antibody targeting HP1 gamma. Anti-HP1 gamma Antibody (3Y560) can be used in WB, IHC-P, IHC-Fr, IF.

Anti-HP1 gamma Antibody (3Y560)

Copy Product Info
🥰Excellent
Catalog No. TMAB-07266

Anti-HP1 gamma Antibody (3Y560) is a Mouse antibody targeting HP1 gamma. Anti-HP1 gamma Antibody (3Y560) can be used in WB, IHC-P, IHC-Fr, IF.

Anti-HP1 gamma Antibody
(3Y560)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HP1 gamma Antibody (3Y560) is a Mouse antibody targeting HP1 gamma. Anti-HP1 gamma Antibody (3Y560) can be used in WB, IHC-P, IHC-Fr, IF.
Ig Type
IgG
Clone
3Y560
Reactivity
Human
Verified Activity
Sample:
K562 (Human) Cell Lysate at 30 ug
HL60 (Human) Cell Lysate at 30 ug
MOLT-4 (Human) Cell Lysate at 30 ug
Primary: Anti-HP1 gamma (TMAB-07266) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 21 kD
Observed band size: 21 kD
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationNucleus (Potential). Note=Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential).
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundHP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Antigen Details
Immunogen
Recombinant Protein: human HP1 gamma Protein
Antigen Species
Human
Gene Name
CBX3
Gene ID
Protein Name
Chromobox protein homolog 3
Uniprot ID
Function
Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Chemical Properties
Molecular WeightTheoretical: 21 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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