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Anti-HP1 gamma Antibody (3Y560)
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Catalog No. TMAB-07266
Anti-HP1 gamma Antibody (3Y560) is a Mouse antibody targeting HP1 gamma. Anti-HP1 gamma Antibody (3Y560) can be used in WB, IHC-P, IHC-Fr, IF.
Anti-HP1 gamma Antibody (3Y560)
Anti-HP1 gamma Antibody (3Y560)
Copy Product Info😃Good
Catalog No. TMAB-07266
Anti-HP1 gamma Antibody (3Y560) is a Mouse antibody targeting HP1 gamma. Anti-HP1 gamma Antibody (3Y560) can be used in WB, IHC-P, IHC-Fr, IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Antigen Details
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| Description | Anti-HP1 gamma Antibody (3Y560) is a Mouse antibody targeting HP1 gamma. Anti-HP1 gamma Antibody (3Y560) can be used in WB, IHC-P, IHC-Fr, IF. |
| Ig Type | IgG |
| Clone | 3Y560 |
| Reactivity | Human |
| Verified Activity | Sample: K562 (Human) Cell Lysate at 30 ug HL60 (Human) Cell Lysate at 30 ug MOLT-4 (Human) Cell Lysate at 30 ug Primary: Anti-HP1 gamma (TMAB-07266) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 21 kD Observed band size: 21 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus (Potential). Note=Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential). |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | HP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Immunogen | Recombinant Protein: human HP1 gamma Protein |
| Antigen Species | Human |
| Gene Name | CBX3 |
| Gene ID | |
| Protein Name | Chromobox protein homolog 3 |
| Uniprot ID | |
| Function | Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Molecular Weight | Theoretical: 21 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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