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Anti-HLA-F Monoclonal Antibody (7N518)
(Synonyms: HLAF, HLA-CDA12, HLA-5.4, CDA12) Copy Product Info
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Synonyms: HLAF, HLA-CDA12, HLA-5.4, CDA12
Catalog No. TMAT-0969 Copy Product Info
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Anti-HLA-F Monoclonal Antibody (7N518) is a Mouse antibody targeting HLA-F. Anti-HLA-F Monoclonal Antibody (7N518) can be used in WB,FCM.
Anti-HLA-F Monoclonal Antibody
(7N518)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-HLA-F Monoclonal Antibody (7N518) is a Mouse antibody targeting HLA-F. Anti-HLA-F Monoclonal Antibody (7N518) can be used in WB,FCM. |
| Synonyms | HLAF, HLA-CDA12, HLA-5.4, CDA12 |
| Ig Type | IgG2b |
| Clone | 7N518 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human HLA-F (AA: 22-305) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | HLA-F |
| Gene ID | |
| Protein Name | HLA class I histocompatibility antigen, alpha chain F |
| Uniprot ID |
| Molecular Weight | Theoretical: 39 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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