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Synonyms: HLA-DPB, HLA-DP1B, HLA-DP, DPB1
Anti-HLA-DPB1 Monoclonal Antibody
(4N91)

| Description | Anti-HLA-DPB1 Monoclonal Antibody (4N91) is a Mouse antibody targeting HLA-DPB1. Anti-HLA-DPB1 Monoclonal Antibody (4N91) can be used in IHC,FCM. |
| Synonyms | HLA-DPB, HLA-DP1B, HLA-DP, DPB1 |
| Ig Type | IgG1 |
| Clone | 4N91 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human HLA-DPB1 (AA: extra 30-215) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | HLA-DPB1 |
| Gene ID | |
| Protein Name | HLA class II histocompatibility antigen, DP beta 1 chain |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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