Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-HLA-C Monoclonal Antibody (1M284)
(Synonyms: PSORS1, MHC, HLC-C, HLA-JY3, HLAC, D6S204) Copy Product Info
😃Good
Synonyms: PSORS1, MHC, HLC-C, HLA-JY3, HLAC, D6S204
Catalog No. TMAT-0794 Copy Product Info
😃Good
Anti-HLA-C Monoclonal Antibody (1M284) is a Mouse antibody targeting HLA-C. Anti-HLA-C Monoclonal Antibody (1M284) can be used in IHC,IF,FCM.
Anti-HLA-C Monoclonal Antibody
(1M284)
Product information is being updated, if you want to purchase, please click the bulk custom button.
Add to Quotation
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-HLA-C Monoclonal Antibody (1M284) is a Mouse antibody targeting HLA-C. Anti-HLA-C Monoclonal Antibody (1M284) can be used in IHC,IF,FCM. |
| Synonyms | PSORS1, MHC, HLC-C, HLA-JY3, HLAC, D6S204 |
| Ig Type | IgG1 |
| Clone | 1M284 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/50-1/200; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. About 6000 HLA-C alleles have been described. The HLA system plays an important role in the occurrence and outcome of infectious diseases, including those caused by the malaria parasite, the human immunodeficiency virus (HIV), and the severe acute respiratory syndrome coronavirus (SARS-CoV). The structural spike and the nucleocapsid proteins of the novel coronavirus SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), are reported to contain multiple Class I epitopes with predicted HLA restrictions. Individual HLA genetic variation may help explain different immune responses to a virus across a population. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human HLA-C (AA: 25-308) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | HLA-C |
| Gene ID | |
| Protein Name | HLA class I histocompatibility antigen, C alpha chain |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags:
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.