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Anti-HIF1A Monoclonal Antibody (6E576)
(Synonyms: PASD8, MOP1, HIF1-ALPHA, HIF-1alpha, HIF1A, HIF1, bHLHe78) Copy Product Info
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Synonyms: PASD8, MOP1, HIF1-ALPHA, HIF-1alpha, HIF1A, HIF1, bHLHe78
Catalog No. TMAT-1366 Copy Product Info
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Anti-HIF1A Monoclonal Antibody (6E576) is a Mouse antibody targeting HIF1A. Anti-HIF1A Monoclonal Antibody (6E576) can be used in WB,IHC,IF.
Anti-HIF1A Monoclonal Antibody
(6E576)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-HIF1A Monoclonal Antibody (6E576) is a Mouse antibody targeting HIF1A. Anti-HIF1A Monoclonal Antibody (6E576) can be used in WB,IHC,IF. |
| Synonyms | PASD8, MOP1, HIF1-ALPHA, HIF-1alpha, HIF1A, HIF1, bHLHe78 |
| Ig Type | IgG1 |
| Clone | 6E576 |
| Reactivity | Human,Mouse,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. (provided by RefSeq) Tissue specificity: Expressed in most tissues with highest levels in kidney and heart. Overexpressed in the majority of common human cancers and their metastases, due to the presence of intratumoral hypoxia and as a result of mutations in genes encoding oncoproteins and tumor suppressors. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human HIF1A expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | HIF1A |
| Gene ID | |
| Protein Name | Hypoxia-inducible factor 1-alpha |
| Uniprot ID |
| Molecular Weight | Theoretical: 120 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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