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Synonyms: VSCN2, TKR1, p185(erbB2), NGL, NEU, MLN-19, MLN 19, HER-2/neu, HER-2, ERBB2, c-ERB-2, c-ERB2, CD340
Anti-HER2 Monoclonal Antibody
(5W182)

| Description | Anti-HER2 Monoclonal Antibody (5W182) is a Mouse antibody targeting HER2. Anti-HER2 Monoclonal Antibody (5W182) can be used in IHC. |
| Synonyms | VSCN2, TKR1, p185(erbB2), NGL, NEU, MLN-19, MLN 19, HER-2/neu, HER-2, ERBB2, c-ERB-2, c-ERB2, CD340 |
| Ig Type | IgG2b |
| Clone | 5W182 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | The C-erbB-2 (HER-2/neu) gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. High levels of c-erbB-2 were associated with estrogen receptor (ER) and progesterone receptor negativity. Overexpression of the c-erbB-2 oncogene has been shown to be associated with poor prognosis in ovarian and breast cance, The level of increased Neu expression can be a predictor of disease prognosis |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of HER-2 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ERBB2 |
| Gene ID | |
| Protein Name | Receptor tyrosine-protein kinase erbB-2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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