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Synonyms: RPD3-2, RPD3, HD3
Anti-HDAC3 Monoclonal Antibody
(3B938)

| Description | Anti-HDAC3 Monoclonal Antibody (3B938) is a Mouse antibody targeting HDAC3. Anti-HDAC3 Monoclonal Antibody (3B938) can be used in WB,IF. |
| Synonyms | RPD3-2, RPD3, HD3 |
| Ig Type | IgG2a |
| Clone | 3B938 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | HDAC3 |
| Gene ID | |
| Protein Name | Histone deacetylase 3 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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