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Anti-HDAC3 Monoclonal Antibody (3B938)

(Synonyms: RPD3-2, RPD3, HD3) Copy Product Info
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Synonyms: RPD3-2, RPD3, HD3

Catalog No. TMAT-0518 Copy Product Info
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Anti-HDAC3 Monoclonal Antibody (3B938) is a Mouse antibody targeting HDAC3. Anti-HDAC3 Monoclonal Antibody (3B938) can be used in WB,IF.

Anti-HDAC3 Monoclonal Antibody
(3B938)

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Product Introduction

Bioactivity
Description
Anti-HDAC3 Monoclonal Antibody (3B938) is a Mouse antibody targeting HDAC3. Anti-HDAC3 Monoclonal Antibody (3B938) can be used in WB,IF.
SynonymsRPD3-2, RPD3, HD3
Ig Type
IgG2a
Clone
3B938
Reactivity
Human
Application
Recommended Dose
WB: 1/500-1/2000; IF: 1/200-1/1000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundHDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2. Entrez Protein NC_000005. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human HDAC3 (aa224-428) expressed in E. Coli.
Antigen Species
Human
Gene Name
HDAC3
Gene ID
Protein Name
Histone deacetylase 3
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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