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Synonyms: SECT, HLP, CTSGL1, CTLA1, CSP-B, CSPB, CGL-1, CGL1, CCPI, C11
Anti-GZMB Monoclonal Antibody
(3E182)

| Description | Anti-GZMB Monoclonal Antibody (3E182) is a Mouse antibody targeting GZMB. Anti-GZMB Monoclonal Antibody (3E182) can be used in IHC. |
| Synonyms | SECT, HLP, CTSGL1, CTLA1, CSP-B, CSPB, CGL-1, CGL1, CCPI, C11 |
| Ig Type | IgG2a |
| Clone | 3E182 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human GZMB (AA: 21-247) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | GZMB |
| Gene ID | |
| Protein Name | Granzyme B |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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