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Anti-GITR Monoclonal Antibody (8H287)
(Synonyms: TNFRSF18, GITR-D, CD357, AITR) Copy Product Info
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Synonyms: TNFRSF18, GITR-D, CD357, AITR
Catalog No. TMAT-1643 Copy Product Info
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Anti-GITR Monoclonal Antibody (8H287) is a Mouse antibody targeting GITR. Anti-GITR Monoclonal Antibody (8H287) can be used in FCM.
Anti-GITR Monoclonal Antibody
(8H287)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-GITR Monoclonal Antibody (8H287) is a Mouse antibody targeting GITR. Anti-GITR Monoclonal Antibody (8H287) can be used in FCM. |
| Synonyms | TNFRSF18, GITR-D, CD357, AITR |
| Ig Type | IgG1 |
| Clone | 8H287 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human GITR (AA: 184-241) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TNFRSF18 |
| Gene ID | |
| Protein Name | Tumor necrosis factor receptor superfamily member 18 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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