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Anti-GART Antibody (5T243)
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Catalog No. TMAB-06338
Anti-GART Antibody (5T243) is a Mouse antibody targeting GART. Anti-GART Antibody (5T243) can be used in WB,ICC/IF.
Anti-GART Antibody (5T243)
Anti-GART Antibody (5T243)
Copy Product Info😃Good
Catalog No. TMAB-06338
Anti-GART Antibody (5T243) is a Mouse antibody targeting GART. Anti-GART Antibody (5T243) can be used in WB,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-GART Antibody (5T243) is a Mouse antibody targeting GART. Anti-GART Antibody (5T243) can be used in WB,ICC/IF. |
| Ig Type | IgG1, Kappa |
| Clone | 5T243 |
| Reactivity | Human (predicted:Rat) |
| Verified Activity | Sample: Lane 1: Human HeLa cell lysates Lane 2: Human A431 cell lysates Lane 3: Human HepG2 cell lysates Primary: Anti-GART (TMAB-06338) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 107 kDa Observed band size: 55, 130 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1000; ICC/IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | PBS, Glycerol, BSA. |
| Concentration | 1mg/ml |
| Research Background | Purines are critical for energy metabolism, cell signaling and cell reproduction and also function as precursors for coenzymes, energy transfer molecules, regulatory factors and proteins involved in RNA and DNA synthesis. GART (GAR transformylase), also referred to as AIRS, GARS, PAIS, PGFT, PRGS or GARTF, is 1,010 amino acids in length and is a key folate-dependent trifunctional enzyme with phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase and AICAR (phosphoribosylaminoimidazole synthetase) activity required for de novo purine biosynthesis. Cancer cells require considerable amounts of purines to sustain their accelerated growth and GART is, therefore, a target for cancer chemotherapy. GART is highly conserved in vertebrates. Two isoforms of GART are expressed due to alternative splicing events. |
| Immunogen | KLH conjugated synthetic peptide: human GART |
| Antigen Species | Human |
| Gene Name | GART |
| Gene ID | |
| Protein Name | Trifunctional purine biosynthetic protein adenosine-3 |
| Uniprot ID |
| Molecular Weight | Theoretical: 107 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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