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Anti-GAD2 Monoclonal Antibody (2U499)
(Synonyms: GAD65) Copy Product Info
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Synonyms: GAD65
Catalog No. TMAT-1222 Copy Product Info
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Anti-GAD2 Monoclonal Antibody (2U499) is a Mouse antibody targeting GAD2. Anti-GAD2 Monoclonal Antibody (2U499) can be used in FCM.
Anti-GAD2 Monoclonal Antibody
(2U499)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-GAD2 Monoclonal Antibody (2U499) is a Mouse antibody targeting GAD2. Anti-GAD2 Monoclonal Antibody (2U499) can be used in FCM. |
| Synonyms | GAD65 |
| Ig Type | IgG1 |
| Clone | 2U499 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human GAD2 (AA: 1-100) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | GAD2 |
| Gene ID | |
| Protein Name | Glutamate decarboxylase 2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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