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Anti-GAB2 Monoclonal Antibody (1Z516)

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Catalog No. TMAT-1634 Copy Product Info
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Anti-GAB2 Monoclonal Antibody (1Z516) is a Mouse antibody targeting GAB2. Anti-GAB2 Monoclonal Antibody (1Z516) can be used in IHC,IF,FCM.

Anti-GAB2 Monoclonal Antibody
(1Z516)

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Product Introduction

Bioactivity
Description
Anti-GAB2 Monoclonal Antibody (1Z516) is a Mouse antibody targeting GAB2. Anti-GAB2 Monoclonal Antibody (1Z516) can be used in IHC,IF,FCM.
Ig Type
IgG2a
Clone
1Z516
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide.
Concentration1 mg/mL
Research BackgroundThis gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human GAB2 (AA: 332-476) expressed in E. Coli.
Antigen Species
Human
Gene Name
GAB2
Gene ID
Protein Name
GRB2-associated-binding protein 2
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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