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Anti-FMR1 Monoclonal Antibody (3E455)
(Synonyms: POF1, POF, FRAXA, FMRP) Copy Product Info
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Synonyms: POF1, POF, FRAXA, FMRP
Catalog No. TMAT-1236 Copy Product Info
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Anti-FMR1 Monoclonal Antibody (3E455) is a Mouse antibody targeting FMR1. Anti-FMR1 Monoclonal Antibody (3E455) can be used in WB,IHC,IF.
Anti-FMR1 Monoclonal Antibody
(3E455)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-FMR1 Monoclonal Antibody (3E455) is a Mouse antibody targeting FMR1. Anti-FMR1 Monoclonal Antibody (3E455) can be used in WB,IHC,IF. |
| Synonyms | POF1, POF, FRAXA, FMRP |
| Ig Type | IgG1 |
| Clone | 3E455 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | FMR1, also known as POF, FMRP, FRAXA. Entrez Protein: NP_002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human FMR1 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | FMR1 |
| Gene ID | |
| Protein Name | Fragile X messenger ribonucleoprotein 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 71 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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