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Anti-FLT1 Monoclonal Antibody (8P431)
(Synonyms: VEGFR1, FLT) Copy Product Info
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Synonyms: VEGFR1, FLT
Catalog No. TMAT-0877 Copy Product Info
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Anti-FLT1 Monoclonal Antibody (8P431) is a Mouse antibody targeting FLT1. Anti-FLT1 Monoclonal Antibody (8P431) can be used in FCM.
Anti-FLT1 Monoclonal Antibody
(8P431)
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Product Introduction
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Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-FLT1 Monoclonal Antibody (8P431) is a Mouse antibody targeting FLT1. Anti-FLT1 Monoclonal Antibody (8P431) can be used in FCM. |
| Synonyms | VEGFR1, FLT |
| Ig Type | IgG1 |
| Clone | 8P431 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), also known as FLT1 or VEGFR-1. It is a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells. |
| Antigen Species | Human |
| Gene Name | FLT1 |
| Gene ID | |
| Protein Name | Vascular endothelial growth factor receptor 1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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