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Anti-FGFR3 Monoclonal Antibody (6Z58)
(Synonyms: JTK4, HSFGFR3EX, CEK2, CD333, ACH) Copy Product Info
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Synonyms: JTK4, HSFGFR3EX, CEK2, CD333, ACH
Catalog No. TMAT-0920 Copy Product Info
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Anti-FGFR3 Monoclonal Antibody (6Z58) is a Mouse antibody targeting FGFR3. Anti-FGFR3 Monoclonal Antibody (6Z58) can be used in IHC,FCM.
Anti-FGFR3 Monoclonal Antibody
(6Z58)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-FGFR3 Monoclonal Antibody (6Z58) is a Mouse antibody targeting FGFR3. Anti-FGFR3 Monoclonal Antibody (6Z58) can be used in IHC,FCM. |
| Synonyms | JTK4, HSFGFR3EX, CEK2, CD333, ACH |
| Ig Type | IgG1 |
| Clone | 6Z58 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human FGFR3 (AA: 529-694) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | FGFR3 |
| Gene ID | |
| Protein Name | Fibroblast growth factor receptor 3 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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