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Anti-FGFR1 Monoclonal Antibody (7O81)
(Synonyms: OGD, KAL2, HBGFR, FLT2, FLG, FGFBR, CEK, CD331, BFGFR) Copy Product Info
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Synonyms: OGD, KAL2, HBGFR, FLT2, FLG, FGFBR, CEK, CD331, BFGFR
Catalog No. TMAT-0809 Copy Product Info
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Anti-FGFR1 Monoclonal Antibody (7O81) is a Mouse antibody targeting FGFR1. Anti-FGFR1 Monoclonal Antibody (7O81) can be used in FCM.
Anti-FGFR1 Monoclonal Antibody
(7O81)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-FGFR1 Monoclonal Antibody (7O81) is a Mouse antibody targeting FGFR1. Anti-FGFR1 Monoclonal Antibody (7O81) can be used in FCM. |
| Synonyms | OGD, KAL2, HBGFR, FLT2, FLG, FGFBR, CEK, CD331, BFGFR |
| Ig Type | IgG2b |
| Clone | 7O81 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome. It is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant extracellular fragment of human FGFR1 (aa22-376) fused with hIgGFc tag expressed in HEK293 cells. |
| Antigen Species | Human |
| Gene Name | FGFR1 |
| Gene ID | |
| Protein Name | Fibroblast growth factor receptor 1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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