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Synonyms: MORT1, GIG3
Anti-FADD Monoclonal Antibody
(6B208)

| Description | Anti-FADD Monoclonal Antibody (6B208) is a Mouse antibody targeting FADD. Anti-FADD Monoclonal Antibody (6B208) can be used in FCM. |
| Synonyms | MORT1, GIG3 |
| Ig Type | IgG1 |
| Clone | 6B208 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human FADD (AA: 20-150) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | FADD |
| Gene ID | |
| Protein Name | FAS-associated death domain protein |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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