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Anti-FADD Monoclonal Antibody (6B208)

(Synonyms: MORT1, GIG3) Copy Product Info
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Synonyms: MORT1, GIG3

Catalog No. TMAT-1264 Copy Product Info
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Anti-FADD Monoclonal Antibody (6B208) is a Mouse antibody targeting FADD. Anti-FADD Monoclonal Antibody (6B208) can be used in FCM.

Anti-FADD Monoclonal Antibody
(6B208)

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Product Introduction

Bioactivity
Description
Anti-FADD Monoclonal Antibody (6B208) is a Mouse antibody targeting FADD. Anti-FADD Monoclonal Antibody (6B208) can be used in FCM.
SynonymsMORT1, GIG3
Ig Type
IgG1
Clone
6B208
Reactivity
Human
Application
Recommended Dose
FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThe protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human FADD (AA: 20-150) expressed in E. Coli.
Antigen Species
Human
Gene Name
FADD
Gene ID
Protein Name
FAS-associated death domain protein
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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