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Anti-ERCC1 Monoclonal Antibody (6Q726)
(Synonyms: UV20, RAD10, COFS4) Copy Product Info
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Synonyms: UV20, RAD10, COFS4
Catalog No. TMAT-0744 Copy Product Info
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Anti-ERCC1 Monoclonal Antibody (6Q726) is a Mouse antibody targeting ERCC1. Anti-ERCC1 Monoclonal Antibody (6Q726) can be used in WB,IHC,FCM.
Anti-ERCC1 Monoclonal Antibody
(6Q726)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-ERCC1 Monoclonal Antibody (6Q726) is a Mouse antibody targeting ERCC1. Anti-ERCC1 Monoclonal Antibody (6Q726) can be used in WB,IHC,FCM. |
| Synonyms | UV20, RAD10, COFS4 |
| Ig Type | IgG1 |
| Clone | 6Q726 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ERCC1 (AA: 1-297) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ERCC1 |
| Gene ID | |
| Protein Name | DNA excision repair protein ERCC-1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 32.5 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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