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Anti-ERBB4 Monoclonal Antibody (4H305)
(Synonyms: p180erbB4, HER4, ALS19) Copy Product Info
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Synonyms: p180erbB4, HER4, ALS19
Catalog No. TMAT-1326 Copy Product Info
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Anti-ERBB4 Monoclonal Antibody (4H305) is a Mouse antibody targeting ERBB4. Anti-ERBB4 Monoclonal Antibody (4H305) can be used in IHC,FCM.
Anti-ERBB4 Monoclonal Antibody
(4H305)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-ERBB4 Monoclonal Antibody (4H305) is a Mouse antibody targeting ERBB4. Anti-ERBB4 Monoclonal Antibody (4H305) can be used in IHC,FCM. |
| Synonyms | p180erbB4, HER4, ALS19 |
| Ig Type | IgG1 |
| Clone | 4H305 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ERBB4 (AA: 1159-1308) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ERBB4 |
| Gene ID | |
| Protein Name | Receptor tyrosine-protein kinase erbB-4 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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