Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-ERBB3 Monoclonal Antibody (8G803)
(Synonyms: HER3, c-erbB3) Copy Product Info
😃Good
Synonyms: HER3, c-erbB3
Catalog No. TMAT-0912 Copy Product Info
😃Good
Anti-ERBB3 Monoclonal Antibody (8G803) is a Mouse antibody targeting ERBB3. Anti-ERBB3 Monoclonal Antibody (8G803) can be used in IF.
Anti-ERBB3 Monoclonal Antibody
(8G803)
Product information is being updated, if you want to purchase, please click the bulk custom button.
Add to Quotation
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ERBB3 Monoclonal Antibody (8G803) is a Mouse antibody targeting ERBB3. Anti-ERBB3 Monoclonal Antibody (8G803) can be used in IF. |
| Synonyms | HER3, c-erbB3 |
| Ig Type | IgG1 |
| Clone | 8G803 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | ERBB3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian). It is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant extracellular fragment of human ERBB3 (aa22-369) fused with hIgGFc tag expressed in HEK293 cells. |
| Antigen Species | Human |
| Gene Name | ERBB3 |
| Gene ID | |
| Protein Name | Receptor tyrosine-protein kinase erbB-3 |
| Uniprot ID |
| Molecular Weight | Theoretical: 148 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: Anti-ERBB3 Monoclonal Antibody (8G803) molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.