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Synonyms: EPHA2, ECK
Anti-EPHA2 Monoclonal Antibody
(1N592)

| Description | Anti-EPHA2 Monoclonal Antibody (1N592) is a Mouse antibody targeting EPHA2. Anti-EPHA2 Monoclonal Antibody (1N592) can be used in WB,IHC. |
| Synonyms | EPHA2, ECK |
| Ig Type | IgM |
| Clone | 1N592 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | EPH receptor A2 (EPHA2), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers.EphA2 may serve as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of EphA2 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | EPHA2 |
| Gene ID | |
| Protein Name | Ephrin type-A receptor 2 |
| Uniprot ID |
| Molecular Weight | Theoretical: 108 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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