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Anti-EPHA2 Monoclonal Antibody (1N592)

(Synonyms: EPHA2, ECK) Copy Product Info
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Synonyms: EPHA2, ECK

Catalog No. TMAT-0963 Copy Product Info
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Anti-EPHA2 Monoclonal Antibody (1N592) is a Mouse antibody targeting EPHA2. Anti-EPHA2 Monoclonal Antibody (1N592) can be used in WB,IHC.

Anti-EPHA2 Monoclonal Antibody
(1N592)

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Product Introduction

Bioactivity
Description
Anti-EPHA2 Monoclonal Antibody (1N592) is a Mouse antibody targeting EPHA2. Anti-EPHA2 Monoclonal Antibody (1N592) can be used in WB,IHC.
SynonymsEPHA2, ECK
Ig Type
IgM
Clone
1N592
Reactivity
Human
Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/200-1/1000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationAscitic fluid containing 0.03% sodium azide.
Concentration1 mg/mL
Research BackgroundEPH receptor A2 (EPHA2), with 976-amino acid protein (about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EphA1, EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8, EphA10, EphB1, EphB2, EphB3, EphB4 and EphB6 are Eph family receptors for Ephrin family ligands. In normal cells, EphA2 negatively regulates cell growth and invasiveness. EphA2 is overexpressed by many human cancers, and is often associated with poor prognostic features. The clinical significance of the expression of EphA2 was observed in breast, prostate, colon, skin, cervical, ovarian, and lung cancers.EphA2 may serve as a novel target for bladder cancer, colonic adenocarcinoma and ovarian cancer therapy.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of EphA2 expressed in E. Coli.
Antigen Species
Human
Gene Name
EPHA2
Gene ID
Protein Name
Ephrin type-A receptor 2
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 108 kDa
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-EPHA2 Monoclonal Antibody (1N592) molecular weight