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Anti-EpCAM Antibody (7L675)

Catalog No. TMAB-05607 Copy Product Info
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Anti-EpCAM Antibody (7L675) is a Mouse antibody targeting EpCAM. Anti-EpCAM Antibody (7L675) can be used in WB,ELISA.

Anti-EpCAM Antibody (7L675)

Copy Product Info
🥰Excellent
Catalog No. TMAB-05607

Anti-EpCAM Antibody (7L675) is a Mouse antibody targeting EpCAM. Anti-EpCAM Antibody (7L675) can be used in WB,ELISA.

Anti-EpCAM Antibody
(7L675)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-EpCAM Antibody (7L675) is a Mouse antibody targeting EpCAM. Anti-EpCAM Antibody (7L675) can be used in WB,ELISA.
Ig Type
IgG1
Clone
7L675
Reactivity
Human
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with EpCAM monoclonal antibody, unconjugated (TMAB-05607) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-1000; ELISA: 1:5000-10000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationLateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Co-localizes with CLDN7 at the lateral cell membrane and tight junction.
Tissue SpecificityHighly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human EpCAM
Antigen Species
Human
Gene Name
EPCAM
Gene ID
Protein Name
Epithelial cell adhesion molecule
Uniprot ID
Function
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Chemical Properties
Molecular WeightTheoretical: 35 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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