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Anti-EpCAM Antibody (7L675)

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Catalog No. TMAB-05607

Anti-EpCAM Antibody (7L675) is a Mouse antibody targeting EpCAM. Anti-EpCAM Antibody (7L675) can be used in WB,ELISA.

Anti-EpCAM Antibody (7L675)

Anti-EpCAM Antibody (7L675)

😃Good
Catalog No. TMAB-05607
Anti-EpCAM Antibody (7L675) is a Mouse antibody targeting EpCAM. Anti-EpCAM Antibody (7L675) can be used in WB,ELISA.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2967-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-EpCAM Antibody (7L675) is a Mouse antibody targeting EpCAM. Anti-EpCAM Antibody (7L675) can be used in WB,ELISA.
Ig Type
IgG1
Clone
7L675
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000; ELISA: 1:5000-10000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationLateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Co-localizes with CLDN7 at the lateral cell membrane and tight junction.
Tissue SpecificityHighly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human EpCAM
Antigen Species
Human
Gene Name
EPCAM
Gene ID
Protein Name
Epithelial cell adhesion molecule
Uniprot ID
Function
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Chemical Properties
Molecular WeightTheoretical: 35 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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