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Anti-EIF4EBP1 Antibody (3I395)
😃Good
Catalog No. TMAB-05520
Anti-EIF4EBP1 Antibody (3I395) is a Mouse antibody targeting EIF4EBP1. Anti-EIF4EBP1 Antibody (3I395) can be used in WB.
Anti-EIF4EBP1 Antibody (3I395)
Anti-EIF4EBP1 Antibody (3I395)
😃Good
Catalog No. TMAB-05520
Anti-EIF4EBP1 Antibody (3I395) is a Mouse antibody targeting EIF4EBP1. Anti-EIF4EBP1 Antibody (3I395) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-EIF4EBP1 Antibody (3I395) is a Mouse antibody targeting EIF4EBP1. Anti-EIF4EBP1 Antibody (3I395) can be used in WB. |
| Ig Type | IgG1 |
| Clone | 3I395 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Lung and testis. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]. |
| Immunogen | Recombinant Protein: human EIF4EBP1 |
| Antigen Species | Human |
| Gene Name | EIF4EBP1 |
| Gene ID | |
| Protein Name | Eukaryotic translation initiation factor 4E-binding protein 1 |
| Uniprot ID | |
| Function | Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. |
| Molecular Weight | Theoretical: 12 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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