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Anti-EIF4E Monoclonal Antibody (1J325)
(Synonyms: MGC111573, EIF4F, EIF4EL1, EIF4E1, EIF4E, CBP) Copy Product Info
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Synonyms: MGC111573, EIF4F, EIF4EL1, EIF4E1, EIF4E, CBP
Catalog No. TMAT-0716 Copy Product Info
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Anti-EIF4E Monoclonal Antibody (1J325) is a Mouse antibody targeting EIF4E. Anti-EIF4E Monoclonal Antibody (1J325) can be used in WB,IHC,IF,FCM.
Anti-EIF4E Monoclonal Antibody
(1J325)
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-EIF4E Monoclonal Antibody (1J325) is a Mouse antibody targeting EIF4E. Anti-EIF4E Monoclonal Antibody (1J325) can be used in WB,IHC,IF,FCM. |
| Synonyms | MGC111573, EIF4F, EIF4EL1, EIF4E1, EIF4E, CBP |
| Ig Type | IgG1 |
| Clone | 1J325 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human EIF4E expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | EIF4E |
| Gene ID | |
| Protein Name | Eukaryotic translation initiation factor 4E |
| Uniprot ID |
| Molecular Weight | Theoretical: 25 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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