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Anti-Dynamin-1 Monoclonal Antibody (2R926)

(Synonyms: DNM1, DNM) Copy Product Info
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Synonyms: DNM1, DNM

Catalog No. TMAT-1221 Copy Product Info
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Anti-Dynamin-1 Monoclonal Antibody (2R926) is a Mouse antibody targeting Dynamin-1. Anti-Dynamin-1 Monoclonal Antibody (2R926) can be used in WB,IHC.

Anti-Dynamin-1 Monoclonal Antibody
(2R926)

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Product Introduction

Bioactivity
Description
Anti-Dynamin-1 Monoclonal Antibody (2R926) is a Mouse antibody targeting Dynamin-1. Anti-Dynamin-1 Monoclonal Antibody (2R926) can be used in WB,IHC.
SynonymsDNM1, DNM
Ig Type
IgG2a
Clone
2R926
Reactivity
Human
Application
Recommended Dose
WB: 1/500-1/2000; IHC: 1/200-1/1000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationAscitic fluid containing 0.03% sodium azide.
Concentration1 mg/mL
Research BackgroundDynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human Dynamin-1 expressed in E. Coli.
Antigen Species
Human
Gene Name
DNM1
Gene ID
Protein Name
Dynamin-1
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 97 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-Dynamin-1 Monoclonal Antibody (2R926) molecular weight