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Synonyms: PVA, CDHF6
Anti-DSG3 Monoclonal Antibody
(6J496)

| Description | Anti-DSG3 Monoclonal Antibody (6J496) is a Mouse antibody targeting DSG3. Anti-DSG3 Monoclonal Antibody (6J496) can be used in WB,IHC,FCM. |
| Synonyms | PVA, CDHF6 |
| Ig Type | IgG1 |
| Clone | 6J496 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human DSG3 (AA: 55-159) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | DSG3 |
| Gene ID | |
| Protein Name | Desmoglein-3 |
| Uniprot ID |
| Molecular Weight | Theoretical: 107.5 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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