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Anti-DOC2 Monoclonal Antibody (4Q668)
(Synonyms: DOC-2, DAB2) Copy Product Info
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Synonyms: DOC-2, DAB2
Catalog No. TMAT-1177 Copy Product Info
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Anti-DOC2 Monoclonal Antibody (4Q668) is a Mouse antibody targeting DOC2. Anti-DOC2 Monoclonal Antibody (4Q668) can be used in IF,FCM.
Anti-DOC2 Monoclonal Antibody
(4Q668)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-DOC2 Monoclonal Antibody (4Q668) is a Mouse antibody targeting DOC2. Anti-DOC2 Monoclonal Antibody (4Q668) can be used in IF,FCM. |
| Synonyms | DOC-2, DAB2 |
| Ig Type | IgG1 |
| Clone | 4Q668 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human DOC2 (AA: 652-749) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | DAB2 |
| Gene ID | |
| Protein Name | Disabled homolog 2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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