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Synonyms: LCCS5, DYNII, DYN2, DI-CMTB, CMTDIB, CMTDI1, CMT2M
Anti-DNM2 Monoclonal Antibody
(4U65)

| Description | Anti-DNM2 Monoclonal Antibody (4U65) is a Mouse antibody targeting DNM2. Anti-DNM2 Monoclonal Antibody (4U65) can be used in IHC. |
| Synonyms | LCCS5, DYNII, DYN2, DI-CMTB, CMTDIB, CMTDI1, CMT2M |
| Ig Type | IgG2a |
| Clone | 4U65 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Dynamin-2 (Dyn2), with 870-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin 1 is expressed exclusively in neurons, Dynamin 2 is ubiquitously expressed and Dynamin 3 is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of Dynamin-2 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | DNM2 |
| Gene ID | |
| Protein Name | Dynamin-2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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