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Synonyms: LCCS5, DYNII, DYN2, DI-CMTB, CMTDIB, CMTDI1, CMT2M
Anti-DNM2 Monoclonal Antibody
(3K522)

| Description | Anti-DNM2 Monoclonal Antibody (3K522) is a Mouse antibody targeting DNM2. Anti-DNM2 Monoclonal Antibody (3K522) can be used in WB,FCM. |
| Synonyms | LCCS5, DYNII, DYN2, DI-CMTB, CMTDIB, CMTDI1, CMT2M |
| Ig Type | IgG2a |
| Clone | 3K522 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/250-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human Dynamin-2 (AA: 520-744) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | DNM2 |
| Gene ID | |
| Protein Name | Dynamin-2 |
| Uniprot ID |
| Molecular Weight | Theoretical: 98 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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