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Anti-DFFA Monoclonal Antibody (8J396)
(Synonyms: ICAD, DFF-45, DFF1) Copy Product Info
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Synonyms: ICAD, DFF-45, DFF1
Catalog No. TMAT-0496 Copy Product Info
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Anti-DFFA Monoclonal Antibody (8J396) is a Mouse antibody targeting DFFA. Anti-DFFA Monoclonal Antibody (8J396) can be used in FCM.
Anti-DFFA Monoclonal Antibody
(8J396)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-DFFA Monoclonal Antibody (8J396) is a Mouse antibody targeting DFFA. Anti-DFFA Monoclonal Antibody (8J396) can be used in FCM. |
| Synonyms | ICAD, DFF-45, DFF1 |
| Ig Type | IgG1 |
| Clone | 8J396 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human DFFA (AA: 179-331) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | DFFA |
| Gene ID | |
| Protein Name | DNA fragmentation factor subunit alpha |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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