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Anti-CYP7A1 Antibody (5U571)
😃Good
Catalog No. TMAB-04905
Anti-CYP7A1 Antibody (5U571) is a Mouse antibody targeting CYP7A1. Anti-CYP7A1 Antibody (5U571) can be used in IHC-P,IHC-Fr,IF.
Anti-CYP7A1 Antibody (5U571)
Anti-CYP7A1 Antibody (5U571)
😃Good
Catalog No. TMAB-04905
Anti-CYP7A1 Antibody (5U571) is a Mouse antibody targeting CYP7A1. Anti-CYP7A1 Antibody (5U571) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CYP7A1 Antibody (5U571) is a Mouse antibody targeting CYP7A1. Anti-CYP7A1 Antibody (5U571) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 5U571 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| Tissue Specificity | Detected in liver. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq, Feb 2010]. |
| Immunogen | Recombinant Protein: human CYP7A1 protein |
| Antigen Species | Human |
| Gene Name | CYP7A1 |
| Gene ID | |
| Protein Name | Cytochrome P450 7A1 |
| Uniprot ID | |
| Function | Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis. |
| Molecular Weight | Theoretical: 55 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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