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Anti-Cyclooxygenase 2 Antibody (8F586)

Catalog No. TMAB-04850 Copy Product Info
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Anti-Cyclooxygenase 2 Antibody (8F586) is a Mouse antibody targeting Cyclooxygenase 2. Anti-Cyclooxygenase 2 Antibody (8F586) can be used in WB.

Anti-Cyclooxygenase 2 Antibody (8F586)

Copy Product Info
🥰Excellent
Catalog No. TMAB-04850

Anti-Cyclooxygenase 2 Antibody (8F586) is a Mouse antibody targeting Cyclooxygenase 2. Anti-Cyclooxygenase 2 Antibody (8F586) can be used in WB.

Anti-Cyclooxygenase 2 Antibody
(8F586)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Cyclooxygenase 2 Antibody (8F586) is a Mouse antibody targeting Cyclooxygenase 2. Anti-Cyclooxygenase 2 Antibody (8F586) can be used in WB.
Ig Type
IgG
Clone
8F586
Reactivity
Human
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with Cyclooxygenase 2 monoclonal antibody, unconjugated (TMAB-04850) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMicrosome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Post-translational modifications : S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundProstaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Cyclooxygenase 2
Antigen Species
Human
Gene Name
Ptgs2
Gene ID
Protein Name
Prostaglandin G/H synthase 2
Uniprot ID
Function
Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.
Chemical Properties
Molecular WeightTheoretical: 65 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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