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Anti-CTNNB1 Monoclonal Antibody (3Q66)
(Synonyms: MRD19, CTNNB, Beta-catenin, armadillo) Copy Product Info
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Synonyms: MRD19, CTNNB, Beta-catenin, armadillo
Catalog No. TMAT-0986 Copy Product Info
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Anti-CTNNB1 Monoclonal Antibody (3Q66) is a Mouse antibody targeting CTNNB1. Anti-CTNNB1 Monoclonal Antibody (3Q66) can be used in WB,IHC,FCM.
Anti-CTNNB1 Monoclonal Antibody
(3Q66)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-CTNNB1 Monoclonal Antibody (3Q66) is a Mouse antibody targeting CTNNB1. Anti-CTNNB1 Monoclonal Antibody (3Q66) can be used in WB,IHC,FCM. |
| Synonyms | MRD19, CTNNB, Beta-catenin, armadillo |
| Ig Type | IgG1 |
| Clone | 3Q66 |
| Reactivity | Human,Mouse,Rat,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CTNNB1 (AA: 632-781) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CTNNB1 |
| Gene ID | |
| Protein Name | Catenin beta-1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 85.5 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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