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Anti-CSNK2A2 Monoclonal Antibody (1R19)
(Synonyms: FLJ43934, CSNK2A1, CK2A2) Copy Product Info
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Synonyms: FLJ43934, CSNK2A1, CK2A2
Catalog No. TMAT-0893 Copy Product Info
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Anti-CSNK2A2 Monoclonal Antibody (1R19) is a Mouse antibody targeting CSNK2A2. Anti-CSNK2A2 Monoclonal Antibody (1R19) can be used in WB,IHC,FCM.
Anti-CSNK2A2 Monoclonal Antibody
(1R19)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-CSNK2A2 Monoclonal Antibody (1R19) is a Mouse antibody targeting CSNK2A2. Anti-CSNK2A2 Monoclonal Antibody (1R19) can be used in WB,IHC,FCM. |
| Synonyms | FLJ43934, CSNK2A1, CK2A2 |
| Ig Type | IgG1 |
| Clone | 1R19 |
| Reactivity | Human,Mouse,Rat,Monkey,Rabbit |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/100-1/500; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2 functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alpha and alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits are catalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to the alpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteins implicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thought to influence Wnt signaling via beta-catenin phosphorylation and the PI 3-K signaling pathway via the phosphorylation of Akt. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CSNK2A2 (AA: 194-350) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CSNK2A2 |
| Gene ID | |
| Protein Name | Casein kinase II subunit alpha' |
| Uniprot ID |
| Molecular Weight | Theoretical: 41.2 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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