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Anti-CSK Monoclonal Antibody (8X594)
(Synonyms: MGC117393, CSK) Copy Product Info
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Synonyms: MGC117393, CSK
Catalog No. TMAT-1021 Copy Product Info
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Anti-CSK Monoclonal Antibody (8X594) is a Mouse antibody targeting CSK. Anti-CSK Monoclonal Antibody (8X594) can be used in WB,IF,FCM.
Anti-CSK Monoclonal Antibody
(8X594)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CSK Monoclonal Antibody (8X594) is a Mouse antibody targeting CSK. Anti-CSK Monoclonal Antibody (8X594) can be used in WB,IF,FCM. |
| Synonyms | MGC117393, CSK |
| Ig Type | IgG1 |
| Clone | 8X594 |
| Reactivity | Human,Mouse,Monkey,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Carboxy-terminal Src kinase (Csk) is a ubiquitously expressed nonreceptor tyrosine kinase that negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine. Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK . This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive. The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk .Tissue specificity: Expressed in lung and macrophages. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CSK expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CSK |
| Gene ID | |
| Protein Name | Tyrosine-protein kinase CSK |
| Uniprot ID |
| Molecular Weight | Theoretical: 50 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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