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Anti-CSF1R Monoclonal Antibody (8Z446)
(Synonyms: M-CSF-R, HDLS, FMS, FIM2, CSFR, CSF-1R, C-FMS, CD115) Copy Product Info
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Synonyms: M-CSF-R, HDLS, FMS, FIM2, CSFR, CSF-1R, C-FMS, CD115
Catalog No. TMAT-0734 Copy Product Info
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Anti-CSF1R Monoclonal Antibody (8Z446) is a Mouse antibody targeting CSF1R. Anti-CSF1R Monoclonal Antibody (8Z446) can be used in IHC,FCM.
Anti-CSF1R Monoclonal Antibody
(8Z446)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-CSF1R Monoclonal Antibody (8Z446) is a Mouse antibody targeting CSF1R. Anti-CSF1R Monoclonal Antibody (8Z446) can be used in IHC,FCM. |
| Synonyms | M-CSF-R, HDLS, FMS, FIM2, CSFR, CSF-1R, C-FMS, CD115 |
| Ig Type | IgG2b |
| Clone | 8Z446 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CSF1R (AA: 344-497) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CSF1R |
| Gene ID | |
| Protein Name | Macrophage colony-stimulating factor 1 receptor |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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