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Anti-CRTC3 Monoclonal Antibody (7L519)
(Synonyms: TORC3, FLJ21868, CRTC3) Copy Product Info
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Synonyms: TORC3, FLJ21868, CRTC3
Catalog No. TMAT-1393 Copy Product Info
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Anti-CRTC3 Monoclonal Antibody (7L519) is a Mouse antibody targeting CRTC3. Anti-CRTC3 Monoclonal Antibody (7L519) can be used in WB,IHC,IF.
Anti-CRTC3 Monoclonal Antibody
(7L519)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-CRTC3 Monoclonal Antibody (7L519) is a Mouse antibody targeting CRTC3. Anti-CRTC3 Monoclonal Antibody (7L519) can be used in WB,IHC,IF. |
| Synonyms | TORC3, FLJ21868, CRTC3 |
| Ig Type | IgG1 |
| Clone | 7L519 |
| Reactivity | Human,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CRTC3 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CRTC3 |
| Gene ID | |
| Protein Name | CREB-regulated transcription coactivator 3 |
| Uniprot ID |
| Molecular Weight | Theoretical: 68 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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