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Anti-Collagen II Antibody (2B530)

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Catalog No. TMAB-04521

Anti-Collagen II Antibody (2B530) is a Mouse antibody targeting Collagen II. Anti-Collagen II Antibody (2B530) can be used in IHC-P,IHC-Fr,IF.

Anti-Collagen II Antibody (2B530)

Anti-Collagen II Antibody (2B530)

😃Good
Catalog No. TMAB-04521
Anti-Collagen II Antibody (2B530) is a Mouse antibody targeting Collagen II. Anti-Collagen II Antibody (2B530) can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Collagen II Antibody (2B530) is a Mouse antibody targeting Collagen II. Anti-Collagen II Antibody (2B530) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG1, k
Clone
2B530
Reactivity
Rat (predicted:Mouse)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationSecreted, extracellular space, extracellular matrix.
Tissue SpecificityIsoform 2 is highly expressed in juvenile chondrocyte and low in fetal chondrocyte.
ConstructionHybridoma Monoclonal Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse Collagen II
Antigen Species
Mouse
Gene Name
COL2A1
Gene ID
12824
Protein Name
Procollagen Type II N-Terminal Propeptide
Uniprot ID
P28481
Function
Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
Chemical Properties
Molecular WeightTheoretical: 142 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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