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Anti-COL1A1 Monoclonal Antibody (8M442)
(Synonyms: OI4, OI3, OI2, OI1, EDSC, EDSARTH1) Copy Product Info
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Synonyms: OI4, OI3, OI2, OI1, EDSC, EDSARTH1
Catalog No. TMAT-0652 Copy Product Info
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Anti-COL1A1 Monoclonal Antibody (8M442) is a Mouse antibody targeting COL1A1. Anti-COL1A1 Monoclonal Antibody (8M442) can be used in FCM.
Anti-COL1A1 Monoclonal Antibody
(8M442)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-COL1A1 Monoclonal Antibody (8M442) is a Mouse antibody targeting COL1A1. Anti-COL1A1 Monoclonal Antibody (8M442) can be used in FCM. |
| Synonyms | OI4, OI3, OI2, OI1, EDSC, EDSARTH1 |
| Ig Type | IgG1 |
| Clone | 8M442 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human COL1A1 (AA: 1219-1464) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | COL1A1 |
| Gene ID | |
| Protein Name | Collagen alpha-1(I) chain |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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