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Anti-Claudin6 Antibody (6A290)

😃Good
Catalog No. TMAY-02829
Alias UNQ757/PRO1488, Claudin 6

Anti-Claudin6 Antibody (6A290) is a Mouse antibody targeting Claudin6. Anti-Claudin6 Antibody (6A290) can be used in WB.

Anti-Claudin6 Antibody (6A290)

Anti-Claudin6 Antibody (6A290)

😃Good
Catalog No. TMAY-02829Alias UNQ757/PRO1488, Claudin 6
Anti-Claudin6 Antibody (6A290) is a Mouse antibody targeting Claudin6. Anti-Claudin6 Antibody (6A290) can be used in WB.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Claudin6 Antibody (6A290) is a Mouse antibody targeting Claudin6. Anti-Claudin6 Antibody (6A290) can be used in WB.
AliasUNQ757/PRO1488, Claudin 6
Ig Type
Monoclonal Mouse IgG2a
Clone
6A290
Reactivity
Human
Verified Activity
Anti-Claudin-6 mouse monoclonal antibody at 1:1000 dilution.

-Lane A: Recombinant Human Claudin-6 Protein, VLP 500ng

-Lane B: Virus-Like Particle (VLP) isotype control Protein 500ng

-Secondary

-Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution.

-Developed using the ECL technique.

-Performed under reducing conditions.
Application
WB
Recommended Dose
WB: 1:500-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with Human Claudin6 mRNA. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundClaudin-6 (CLDN6) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and intracellular N and C tails. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. The CLDN6 gene is adjacent to another family member, CLDN9, on chromosome 16. Certain CLDN6-positive cancers, encompassing ovarian, endometrial, and testicular malignancies, have been shown to have their proliferation and invasiveness suppressed upon CLDN6 silencing.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Human Claudin6 mRNA
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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