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Anti-Claudin6 Antibody (6A290)
😃Good
Catalog No. TMAY-02829
Alias UNQ757/PRO1488, Claudin 6
Anti-Claudin6 Antibody (6A290) is a Mouse antibody targeting Claudin6. Anti-Claudin6 Antibody (6A290) can be used in WB.
Anti-Claudin6 Antibody (6A290)
Anti-Claudin6 Antibody (6A290)
😃Good
Catalog No. TMAY-02829Alias UNQ757/PRO1488, Claudin 6
Anti-Claudin6 Antibody (6A290) is a Mouse antibody targeting Claudin6. Anti-Claudin6 Antibody (6A290) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Claudin6 Antibody (6A290) is a Mouse antibody targeting Claudin6. Anti-Claudin6 Antibody (6A290) can be used in WB. |
| Synonyms | UNQ757/PRO1488, Claudin 6 |
| Ig Type | Mouse IgG2a |
| Clone | 6A290 |
| Reactivity | Human |
| Specificity | Human Claudin6 |
| Verified Activity | Anti-Claudin-6 mouse monoclonal antibody at 1:1000 dilution. -Lane A: Recombinant Human Claudin-6 Protein, VLP 500ng -Lane B: Virus-Like Particle (VLP) isotype control Protein 500ng -Secondary -Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. |
| Application | |
| Recommended Dose | WB: 1:500-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with Human Claudin6 mRNA. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Claudin-6 (CLDN6) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and intracellular N and C tails. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. The CLDN6 gene is adjacent to another family member, CLDN9, on chromosome 16. Certain CLDN6-positive cancers, encompassing ovarian, endometrial, and testicular malignancies, have been shown to have their proliferation and invasiveness suppressed upon CLDN6 silencing. |
| Conjucates | Unconjugated |
| Immunogen | Human Claudin6 mRNA |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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