Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-Claudin6 Antibody (6A290) is a Mouse antibody targeting Claudin6. Anti-Claudin6 Antibody (6A290) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Anti-Claudin6 Antibody (6A290) is a Mouse antibody targeting Claudin6. Anti-Claudin6 Antibody (6A290) can be used in WB. |
Alias | UNQ757/PRO1488, Claudin 6 |
Ig Type | Monoclonal Mouse IgG2a |
Clone | 6A290 |
Reactivity | Human |
Verified Activity | Anti-Claudin-6 mouse monoclonal antibody at 1:1000 dilution. -Lane A: Recombinant Human Claudin-6 Protein, VLP 500ng -Lane B: Virus-Like Particle (VLP) isotype control Protein 500ng -Secondary -Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. |
Application | WB |
Recommended Dose | WB: 1:500-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with Human Claudin6 mRNA. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Claudin-6 (CLDN6) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and intracellular N and C tails. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. The CLDN6 gene is adjacent to another family member, CLDN9, on chromosome 16. Certain CLDN6-positive cancers, encompassing ovarian, endometrial, and testicular malignancies, have been shown to have their proliferation and invasiveness suppressed upon CLDN6 silencing. |
Conjucates | Unconjugated |
Immunogen | Human Claudin6 mRNA |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.