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Anti-CK18 Antibody (2A807) (ready to use)
Catalog No. TMAB-04397 Copy Product Info
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Anti-CK18 Antibody (2A807) is a Mouse antibody targeting CK18. Anti-CK18 Antibody (2A807) can be used in IHC-P,IHC-Fr,IF.
Anti-CK18 Antibody (2A807) (ready to use)
Copy Product Info🥰Excellent
Catalog No. TMAB-04397
Anti-CK18 Antibody (2A807) is a Mouse antibody targeting CK18. Anti-CK18 Antibody (2A807) can be used in IHC-P,IHC-Fr,IF.
Anti-CK18 Antibody
(2A807)
(ready to use)
(2A807)
(ready to use)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 3 mL | $104 | 7-10 days | 7-10 days | |
| 6 mL | $184 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CK18 Antibody (2A807) is a Mouse antibody targeting CK18. Anti-CK18 Antibody (2A807) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 2A807 |
| Reactivity | Human |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (human pancreatic carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CK18) Polyclonal Antibody, Unconjugated (TMAB-04397) overnight at 4°C, followed by operating according to SP Kit (Mouse) instructions and DAB staining. |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm, perinuclear region. Nucleus, nucleolus. |
| Tissue Specificity | Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300. |
| Research Background | KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human CK18 |
| Antigen Species | Human |
| Gene Name | KRT18 |
| Gene ID | |
| Protein Name | Keratin, type I cytoskeletal 18 |
| Uniprot ID | |
| Function | When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. |
| Molecular Weight | Theoretical: 48 kDa. |
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
| Transport | Shipping with blue ice. |
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