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Anti-CK14 Antibody (7E955) is a Mouse antibody targeting CK14. Anti-CK14 Antibody (7E955) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 3 mL | $86 | 7-10 days | 7-10 days | |
| 6 mL | $163 | 7-10 days | 7-10 days |
| Description | Anti-CK14 Antibody (7E955) is a Mouse antibody targeting CK14. Anti-CK14 Antibody (7E955) can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG1 |
| Clone | 7E955 |
| Reactivity | Human |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern. |
| Tissue Specificity | Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300. |
| Research Background | This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq]. |
| Immunogen | human CK14 |
| Antigen Species | Human |
| Gene Name | KRT14 |
| Gene ID | |
| Protein Name | Keratin, type I cytoskeletal 14 |
| Uniprot ID | |
| Function | The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. |
| Molecular Weight | Theoretical: 52 kDa. |
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
| Transport | Shipping with blue ice. |
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